Endocrinology/Carrier proteins

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Mostly see lecture 7 objectives for coverage of the carrier proteins.

The gist is that lipid-soluble hormones tend to be bound to carrier proteins to increase their solubility in plasma and prolong their half-lives. Most hormones have their own carrier proteins. Those that don't are bound to other, perhaps unexpected, carriers such as albumin.

Hormones that bind albumin:

  • aldosterone (50% bound)
  • testosterone (also binds TeBG)
  • retinoic acid
  • estrone

Hormones that bind TeBG:

  • estradiol

Hormones that bind CBG:

  • cortisol
  • progesterone
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